|Today's neuroscience, tomorrow's history- Professor Richard Frackowiak [videorecording] - Frackowiak, Richard S. J|
Professor Richard Frackowiak interviewed by Richard Thomas
Keywords: Oral history; Neurosciences
|Functional compensation of motor function in pre-symptomatic Huntington's disease. (Volume 132) - Kloppel, Stefan|
This article is from Brain, volume 132.AbstractInvoluntary choreiform movements are a clinical hallmark of Huntington's disease. Studies in clinically affected patients suggest a shift of motor activations to parietal cortices in response to progressive neurodegeneration. Here, we studied pre-symptomatic gene carriers to examine the compensatory mechanisms that underlie the phenomenon of retained motor function in the presence of degenerative change...
|The functional neuroimaging correlates of psychogenic versus organic dystonia. (Volume 136) - Schrag, Anette E.|
This article is from Brain, volume 136.AbstractThe neurobiological basis of psychogenic movement disorders remains poorly understood and the management of these conditions difficult. Functional neuroimaging studies have provided some insight into the pathophysiology of disorders implicating particularly the prefrontal cortex, but there are no studies on psychogenic dystonia, and comparisons with findings in organic counterparts are rare...
|Accuracy of dementia diagnosis--a direct comparison between radiologists and a computerized method. (Volume 131) - Kloppel, Stefan|
This article is from Brain, volume 131.AbstractThere has been recent interest in the application of machine learning techniques to neuroimaging-based diagnosis. These methods promise fully automated, standard PC-based clinical decisions, unbiased by variable radiological expertise. We recently used support vector machines (SVMs) to separate sporadic Alzheimer's disease from normal ageing and from fronto-temporal lobar degeneration (FTLD)...